Around 10:00 a.m. Monday, an accident involving a semi and a bus on I-155 shut down the northbound lane in Tazewell County.
An Illinois State Police Official said life flight and four ambulances were called to the scene.
Police believe the semi rear-ended the back corner of the bus.
A bus was called in to escort uninjured passengers off the scene.
Before 1:00 p.m., one lane of traffic was opened up northbound, allowing traffic back through.
The accident remains under investigation by the Illinois State Police.
This story will be updated.